What is Optic Atrophy?

Optic atrophy means damage to the optic nerve which is responsible for transmitting information to or from the brain from or to the eye. It may result from injury, heredity or from certain diseases such as glaucoma. Regardless of the cause, the result is often the same: a marked loss of sight that has marked implications to the functioning of an individual on a daily basis. Since the major traditional treatment plans mostly aim at controlling the symptoms, the search for new treatment modalities such as stem cell therapy is more appropriate.

The Science of Stem Cells

Stem cells remain undifferentiated and as such can transform into a number of specialized cells for instance those required in the mending for damaged tissues. In the context of optic atrophy, stem cells hold promise for several reasons:

1. Cell Replacement: Retinal ganglion cells (RGCs) are the first type of neurons that get killed in optic atrophy and stem cells are used to replace them. The plan is to put working stem cells directly into the optic nerve so that the cells can regrow in its place, thus restoring vision.
2. Neuroprotection: Apart from replacement, stem cells can release proteins or neurotrophic factors, which promote neuron survival and growth. This neuroprotection may also prevent existing nerves cells from degeneration and perhaps even improve their efficiency.
3. Modulation of Inflammation: Inflammation in your optic nerve is likely to cause additional damage than what is already present. Stem cells also have anti-inflammatory effects in their natural state and help calm the inflammation occurring in the optic nerve in this disease.

Patients should consider the following when exploring these options:

1. Consulting Specialists: Talking to professionals involved in regenerative medicine is very important. They can give information of more recent research, estimated therapies and treatments, patient specific care.
2. Evaluating Clinical Trials: Clinical trials can be helpful. They should consider the inclusion criteria opportunities when perusing these options, risks and nature of the study.
3. Understanding the Research: Reading about active research as well as subsequent developments in the field of stem cell therapy can help patients to make informed choices.

The journey toward treatment can often feel overwhelming, but patients can take an active role in their care.

1. Asking Questions: Patients should not shy off from seeking to clarify something about the therapy, the possible impacts of the therapy, negatives and the research done on the therapy among other things.
2. Seeking Support: Patients can pursue different choices in treatment planning, and sharing some experiences will be useful.
3. Setting Realistic Goals: Patients should be realistic over the prospects of stem cell therapy. Successful stem cell therapy enhances the prompt regenerative ability of tissues impaired compared to other well-established medical procedures. Recognizing that there will be dramatic improvements in some and minimal changes in others is a way of managing expectations for a variety of outcomes.

At Eye Stem Cell Center in Yemen, we understand that optic atrophy has powerful perspectives for treatment.

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Optic atrophy

Optic atrophy can often be a challenge to diagnose and treat. Conditions that may cause optic atrophy include; genetic disorder, trauma indispositions and or diseases including glaucoma. As a consequence of the optic nerve damage, retinal ganglion cells (RGC) are lost and these cells play an important role in transferring visual information to the brain. The present treatment regimens are vague and frequently only target the alleviation of symptoms without addressing the disease sources for vision impairment.

Stem Cell Therapy: A New Horizon

Stem cell treatment has become one of the most promising avenues in the search for new vision restoration methods. Stem cells are undifferentiated and renewable cells, in which its greatest promise arises from its capability of developing into specialized cells of the nervous system. Here are several innovative approaches:

1. Cell Replacement Therapy: Scientists use stem cell therapy which helps regenerate lost RGCs. There exists an opportunity of fixing the optic nerve through replacement of damaged stem cells with healthy ones to enhance light conduction.
2. Neuroprotective Strategies: Stem cells can also release proteins that are important to maintain functioning of the neurons that already exist. In the best-case scenario, stem cell therapy could create a micro environmental that sustains RGCs and slows the degeneration of the optic nerve as well as preserve their current functionality. The goal of this approach is not only to rebuild but also to save what is left behind.
3. Gene Therapy Integration: The use of stem cell therapy in conjunction with gene therapy provides treatment that targets the problem from a number of aspects. While performing gene transplantation together with stem cell transplantation, the researchers expect to boost the efficiency of cell survival or regeneration mechanisms. This offers lasting improvements that are anchored on these approaches for treating vision impairment.

The scientific studies

Several patients have been able to regain some of the lost sight and have reported to generally feel better with stem cell therapy. Scientists have found efficient approaches in delivering stem cells to the target sites in order to give the maximum effect. Another key area is the use of iPSCs. Such cells are autologous and therefore provide an individual therapy strategy. Through the conversion of skin or blood cells of a patient to iPSCs, then grow into RGCs, it ensures that there is no rejection of the transplanted cells and a higher chance of success.

A Vision for the Future

The research and development in stemmed cell applications for vision impairment give a new dimension to cure optic atrophy. With every advancement that is made, we are poised on the edge of revolutionary cure that will revolutionalize the future for millions of people. Stem cells can not only keep people from losing their vision, but they can also heal it, which can help patients regain their lives. Therefore, even though optic atrophy is a difficult problem, new stem cell approaches promise a glimmer of hope. At Eye Stem Cell Center Malaysia we go beyond what we can see and be able to approach a future in which the ability to see is attainable for everyone.

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Understanding Your Diagnosis

In order to proceed any further with the treatment plans it is important to get a good grasp of what optic atrophy really means and what it entails.

This condition develops due to it affecting the optic nerve. It may result from a trauma, a disease or a genetic predisposition, besides glaucoma. Every case is individual and the primary root dramatically influences possible therapeutic measures. Spend a few minutes to get a proper consultation from a specialist to get the assessment of your individual case.

Everything You wanted to Know about Stem Cell Therapy for Optic atrophy

Optic atrophy is a field where stem cell therapy is promising. These exploit the body’s natural cell-generating capabilities to try to restore function lost to the condition. Here are several aspects to consider:

1. Regenerative Potential: It has been reported that stem cells can be generated into retinal ganglion cells relevant in the transmission of visual impulses. More studies are still being conducted to establish the success of these cells in terms of the ability to attach and reorganize within optic nerve architecture.
2. Neuroprotective Effects: Aside from re-populating the damaged area, stem cells may secrete neuro trophic factors that will enhance the possible survival of neurons in the affected area, thus improving the healing process.
3. Personalized Approaches: Technological improvement such as use of induced pluripotent stem cells (iPSCs) that entails developing a client specific cell for use as a treatment. This lowers the chances of rejection.
4. Researching Options – Given the complexity and rapid evolution of stem cell therapy, thorough research is essential. Stay Informed which can be done when you subscribe to only credible medical journals and organizations’ websites with data on stem cells.
5. Consult Multiple Experts: It is important not to be fixated with one particular view. Seek advice from a medical professional ranging from ophthalmologists, to eye specialists, as well as independent researchers in order to understand all of the available choices.

Weighing Risks and Benefits

Any medical treatment is going to have its pros and cons. When considering stem cell therapy, take the time to evaluate these aspects:

1. Potential for Improvement: There is need to have certain expectations from the treatment that the therapy can offer.
2. Understand the Risks: As with any procedure, there might be certain infections associated with the process, possible complications or even worsening of the current diseases. It is important to discuss these with a healthcare provider as part of making a proper decision.
3. Emotional and Psychological Factors: Think about how you feel about the choice that you will make.
4. Financial Implications : One of the biggest concerns of stem cell therapy is the financial cost and it can be overwhelming.

Making the Decision

Finally, the choice to go for stem cell treatment for optic atrophy in Oman is exclusive of the patient. It should be made based on the full spectrum of information, adequate thinking, and discussion with doctors. If one takes time to search and think critically, there is always a way to make the right decision towards the best health. Reach out to Eye Stem Cell Cure Oman to gain complete knowledge on stem cell therapy for optic atrophy.

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Understanding Optic Atrophy

Like most other atrophies, optic atrophy can be induced by trauma, glaucoma or other diseases such as multiple sclerosis. Optic nerve makes one lose the ability to convey visual information from the retina to the brain thereby resulting in poor vision or blindness.

Unfortunately, interventions in the form of eyeglasses or surgery, do not correct the damaged nerve and most patients have no option other than being left with their condition. Stem cell therapy is a medical discovery promising individual with cure for this disease. Stem cells are special in that they can develop into different types of cells; such as, cells that can repair damaged tissue.

Types of Stem Cells

Several sources of stem cells are used for optic nerve repair: embryonic stem cells, induced pluripotent stem cells (iPSCs), or neural stem cells. All have their pros and cons, yet they are all aimed at the rehabilitation of the nerve tissues.

Mechanisms of Action

Stem cells can contribute to wound healing in several manners. They can also give rise to retinal ganglion cells which are the cells through which visual signals are transmitted. They can release neurotrophic factors – molecules that are necessary for neurons survival and needful for their growth. They can also slow down further deterioration of existing cells or promote cells’ healing mechanisms. iPSCs (a type of stem cells taken from a patient) have had success in being used to replace the lost cells of the optic nerve through transplantation.

Looking Ahead: A Vision for the Future

Using stem cell therapy and targeting of specific genes, the use of combination therapies and the concept of personalized medicine are some of the potential tools that have been able to catalyze this change. To the patient, restoring vision doesn’t mean simply gaining the ability to see; it means regaining basics such as mobility and freedom.

Conclusion

Stem cell therapy occupies one of the most important positions in the treatment of optic atrophy, to help people who have struggled with vision issues for a long time. Further research into this condition may produce a number of treatment options that can help heal the optic atrophy itself and also the causes of nerve injury. As we advance toward the future, the sight of patients getting their vision back gains ground on attainability.

At Eye Stem Cell Cure centre in Dubai, we have a team of experts who use the power of stem cell therapy to treat optic atrophy.

Our doctors understand the possibilities and complications of using stem cell therapy to treat the condition and educate patients well to enable them to take an educated call on whether to choose the stem cell treatment method to treat their condition.

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Existing therapies are still considered to be very restricted. They are chiefly concerned with alleviating signs and symptoms and preventing the further worsening of disease, but these treatments do not attack the disease’s source or heal any of the destroyed retinal cells. This is where stem cell therapy comes in, to bring new hope and a new way to treat the condition and repair damage.

Science of Stem Cell

Stem cells are special because of their versatility of being able to develop into a number of specialized cells, some of which degenerate in diseases such as RP. Ophthalmology has now the potential to replace or repair retinal cells using stem cells.

Types of Stem Cells which are applied to Retinitis

• Embryonic Stem Cells (ESCs): From early-stage embryos, ESCs are potent stem cells capable of differentiating into all epithelial cell types of the body. Due to their capacity to produce the retinal cells they are of immense benefit in research associated with treatment.
• Induced Pluripotent Stem Cells (iPSCs): These are adult cells which have been coerced to go back to a similar state as embryonic cells. It is noteworthy that iPSCs can be genetically tailored to a patient’s best advantage, which makes these cells appropriate for other types of treatment.

Adult Stem Cells: Existing in several tissues among which the retina, the adult stem cells’ being less versatile in terms of differentiation they have the potential for treating retinal diseases through regeneration and repair.

New and revolutionary developments in stem cell therapy for Retinitis Pigmentosa

The progress in stem cell therapy can be considered as the advancement in methodology for treating RP in London. Here are some of the most exciting advancements:

Retinal Cell Replacement

One of the specific approaches which has a lot of potential is stem cell replacement for the damaged retinal cells. Investigators have managed to derive RPE cells from ESCs and iPSCs to a considerable extent. They play a central role in the preservation of the health of the retina. Transplantation of those cells into the patients’ eyes results in overall positive visual changes as well as disease stabilization.

Eugenics and stem cells

The use of CRISPR/Cas9 and stem cell therapy can be regarded as an innovative idea in the medical field. In contrast to the cure, which attempts to treat the symptoms of retinitis, regeneration know-how makes use of perfectly normal stem cells transplanted into a patient and thereby eradicates the origin of the ailment.

Stem Cell-Derived Retinal Organoids

Retinal organoids are constructed 3D tissue mimics of the retina derived from pluripotent stem cells. These organoids have a close resemblance with human retinal tissue, thus, are beneficial to delve into the root cause of the diseases and also to develop new treatments.

Conclusion

The introduction of stem cell therapy for Retinitis Pigmentosa in London is considered revolutionary in the sphere of vision science. Retinitis pigmentosa is a degenerative eye disease that causes gradual vision loss. For those who face it, the possibility of stem cell’ use is the hope. Stem cell developments do not only contribute toward the progressive alteration of the treatment of retinitis, they are revolutionary. This is how these new discoveries are revolutionizing the lives of RP patients at Eyestemcellcenter in London.

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In the United Arab Emirates (UAE), Retinitis Pigmentosa (RP) presents a unique challenge for individuals grappling with this genetic eye disorder. As the desert sands stretch under the vibrant sun, the gradual deterioration of light-sensitive cells in the retina casts a shadow on the visual landscape of those affected. The progressive loss of peripheral vision, often beginning in adolescence or early adulthood, poses significant hurdles in a region known for its dynamic growth. Amidst the modern architecture and technological advancements, individuals with RP navigate a complex journey, adapting to the narrowing visual field and potential vision loss. The multicultural fabric of the UAE adds layers to this experience, as affected individuals seek understanding and support within diverse communities.

Causes of Retinitis Pigmentosa (RP): –

Retinitis Pigmentosa (RP) is primarily caused by genetic mutations that affect the function of the retina, the light-sensitive tissue at the back of the eye. These mutations can be inherited, passed down from parents to their children. The genes involved in RP play essential roles in the normal functioning and maintenance of the retina’s cells, especially the photoreceptors responsible for capturing light.

While genetic factors are the primary cause, environmental and lifestyle factors may also influence the progression of RP. However, these secondary factors are generally less prominent compared to the genetic underpinnings. As research advances, understanding the complex genetic landscape of Retinitis Pigmentosa becomes crucial for developing targeted therapies and interventions.

Symptoms of Retinitis Pigmentosa (RP): –

Retinitis Pigmentosa (RP) in the United Arab Emirates (UAE) unfolds with distinctive visual symptoms. Individual often experience difficulty seeing in low light, leading to night blindness. As RP progresses, peripheral vision diminishes, creating tunnel vision. The narrowing of the visual field can contribute to challenges in activities like driving or navigating crowded spaces.

Other common symptoms include decreased contrast sensitivity, making it harder to distinguish objects, and an increased sensitivity to glare. Many individuals with RP also notice a decline in color perception. The gradual nature of these symptoms distinguishes RP, with some individuals retaining central vision while peripheral vision declines.

It’s important to note that RP affects individuals differently, and the rate of progression can vary. Regular eye examination and early detection are crucial for managing the impact of RP on daily life.

Diagnosis and tests for Retinitis Pigmentosa: –

Diagnosing Retinitis Pigmentosa (RP) in the United Arab Emirates (UAE) involves a series of examinations and tests conducted by eye care professionals. Here’s an overview of the diagnostic process:

1. Clinical Examination: – The ophthalmologist begins by gathering the patient’s medical history, paying particular attention to any family history of vision issues. A comprehensive eye examination, visual acuity tests, is conducted to assess the overall eye health.
2. Visual Field Testing: – Perimetry tests are employed to evaluate the peripheral vision, crucial for identifying any abnormalities associated with RP.
3. Electroretinogram (ERG): – ERG measures the retina’s response to light stimuli, providing valuable insights into the functionality of the light-sensitive cells.
4. Genetic Testing: – Given the hereditary nature of RP, genetic testing may be recommended to identify specific gene mutations prevalent in the UAE population.
5. Ocular Coherence Tomography: – OCT produces detailed images of the retina, aiding in the assessment of retinal thickness and detecting structural changes.
6. Fluorescein Angiography: – This test involves injecting a dye into the bloodstream to highlight blood vessels in the retina, assisting in the identification of abnormalities.

Treatment for Retinitis Pigmentosa in UAE: –

“Treatment for Retinitis Pigmentosa (RP) in United Arab Emirates (UAE)” currently lack a definitive cure, but various treatments aim to manage its treatments aim to manage its progression and enhance visual function. In conventional approaches, individuals with RP may benefit from low-vision aids, orientation and mobility training, and genetic counseling. Additionally, some may find assistance through electronic devices designed to improve daily tasks. Experimental treatments include gene therapy and stem cell research, holding potential for addressing the underlying genetic and cellular factors. Stem cell treatment holds promise as a potential intervention to replace damaged retinal cells, through it’s still in experimental stages.

Stem Cell Treatment for Retinitis Pigmentosa (RP): –

“Stem cell treatment for Retinitis Pigmentosa” represents a cutting-edge area of research that holds significant promise for individuals facing this progressive vision disorder. Our “Eye Stem Cell center” does stem cell treatment for retinitis pigmentosa and gives very good results. RP is characterized by the gradual degeneration to photoreceptor cells in the retina, leading to impaired vision and, in some cases, eventual blindness. Traditional treatments focus on managing symptoms, as there has been no definitive cure. However, stem cell therapy emerges as a potential game changer, aiming to address the root cause of RP by replacing damaged or lost retinal cells.

Stem cells are unique cells with the remarkable ability to transform into various specialized cell types. In the context of RP, the goal is to use stem cells to degenerated. This process involves careful cultivation and manipulation of stem cell in a laboratory setting before transplantation into the patient’s retina.

One approach to stem cell therapy involves the use of pluripotent stem cells have the capacity to differentiate into any cells to generate functional photoreceptors that can integrate into the existing retinal tissue.

The potential impact of stem cell treatment extends beyond halting RP progression; it offers hope for restoring lost vision and improving the overall quality of life for affected individuals with RP are encouraged to explore conventional treatments, such as low-vision aids and orientation and mobility training, to enhance their daily lives. The goal to ensure that the treatment is not only effective but also safe for individuals with RP.

In conclusion, “Stem cell treatment for Retinitis Pigmentosa” represents a frontier in medical research, holding the promise of addressing the root cause of the condition and potentially restoring vision. Ongoing scientific endeavors in this field bring hope for a future where innovative therapies provide meaningful solutions for those living with RP.

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Advancements in stem cell technology have introduced innovative procedures offering great promise to individuals facing challenges associated with diabetes. Stem cell therapy emerges as a hopeful option for those dealing with diabetic retinopathy or other degenerative conditions linked to diabetes. This state-of-the-art approach holds significant potential to deliver transformative and substantial outcomes for patients.

In the context of diabetic retinopathy, a condition characterized by progressive damage to the retina’s blood vessels due to diabetes, stem cell therapy represents a beacon of hope. This condition poses a risk of vision impairment or even blindness. Stem cell research has paved the way for therapies aimed at repairing and regenerating damaged retinal tissue. Stem cell-based treatments for diabetic retinopathy complications harness the remarkable regenerative abilities of these cells. By introducing stem cells into affected areas, they have the potential to stimulate the growth of new blood vessels, repair damaged nerves, and contribute to the restoration of impaired tissue.

Mesenchymal Stem Cell Effectivity in Case of Retinopathy

Mesenchymal stem cell injections administered through the Retro-bulbar route have emerged as a reliable and effective approach, typically requiring one or two treatment sessions. This method has demonstrated a commendable track record in promoting the regeneration of impaired retinal cells, particularly concerning eye-related ailments. Stem cell therapy offers substantial advantages in managing ocular conditions, instilling hope for patients grappling with these challenges. Its remarkable regenerative potential spans various types of eye cells, including retinal pigment epithelium cells, optic nerve cells, macular cells, and photoreceptor cells.

This unique capability holds immense potential in rejuvenating and repairing damaged eye tissues, potentially leading to improved vision and overall eye health. Stem cell therapy also plays a crucial role in impeding the progression of eye-related diseases by addressing root causes and promoting cellular repair, thereby hindering further degeneration. Furthermore, this intervention aims to stabilize vision decline and, in some cases, may even result in noticeable improvements, ultimately enhancing the overall quality of life for patients.

The Eye Stem Cell Centre specializes in delivering targeted, curative eye treatments designed specifically for diabetic patients with eye complications. This dedicated centre offers therapies tailored to aid individuals in managing diabetic eye issues. Those experiencing such challenges are urged to explore personalized and efficient eye treatments available at the Eye Stem Cell Centre to address their specific concerns effectively.

Eye Stem Cell Center. is a highly reputable company excelling in specialized stem cell therapy and treatment services, earning significant trust.

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THE MAIN PARTS OF EYE ARE

Cornea– It is the transparent, anterior, or front part of our eye. The main function is to refract the light along with the lens.

Lens– It is a transparent, biconvex, lens of an eye. The lens is attached to the ciliary body by ligaments.

Retina– It is the innermost layer of the eye. It is light sensitive and acts as a film of a camera.

Optic nerve- The optic nerve encodes the image data recorded by the retina in the form of neural signals that can be read by the brain.

Retinal pigment epithelium- A sheet of black cells that sit beneath the retina. This sheet supports the retina and has a number of important roles, including processing nutrients.

Disorder or disease occurs when one or more than one of these components gets damaged. Different disorders damage different cells of the eye. Here comes the role of stem cell treatment. Different stem cells or specialized cells are used to cure the damage depending on the type of disorder.

Do you know?

The variety of stem cells present in the eye helps to replace the damaged or worn-out cells. Even blinking damages the surface of eye but it a good thing that stem cell is present to replenish it.

Neuronal degeneration

Neuronal degeneration is the cause of debilitating visual impairment associated with prevalent ocular diseases, such as retinitis pigmentosa (RP), age-related macular degeneration (AMD), retinal detachment, and glaucoma. Neural stem cells may help to restore vision in patients who have these diseases, by repopulating the damaged retina and/or by rescuing retinal neurons from further degeneration.

Retinal disorders

Several diseases are marked by retinal degeneration that eventually leads to blindness. Retinal disorders commonly involve the loss of photoreceptor cells, which depletes the eye’s sensitivity to light. In some retinal disorders, including age-related macular degeneration (AMD), this loss results from the failure of the epithelial cells that form a layer at the back of the retina known as the retinal pigment epithelium (RPE). The RPE keeps photoreceptor cells healthy by cleaning up toxic by-products produced during the reaction with light, as well as by providing nutrients. In retinal disorders in which photoreceptors remain in good shape, the main cause of blindness is degeneration of retinal ganglion cells.

STEM CELL THERAPY

Here the question comes can blindness be cured?

You might have heard about stem cell therapy and wondered if it could help you or someone you know who is living with vision loss. To help answer your questions, we’ve put together some information about stem cell treatment and how it helps to cure blindness.

Stem cell therapy for eye is getting headlines as they are the potential to cure diseases for which there are no other treatments. Stem cell treatment for eye is collecting a lot of attention because of its success rate.

Stem-cell therapy could potentially cure blindness even in the late stages of the disease. Because stem cells can be coaxed into becoming any type of cell, they could be used to grow fresh retinal cells for transplantation into the eye to replace those that have been lost.

THREE MAIN TYPES OF STEM CELLS ARE USED IN-vision Treatment

Embryonic stem cells (ESCs)

Embryonic stem cells (ESCs) are pluripotent it means they can become any type of cell in the body. Because of this ability, ESCs have been very important in stem cell therapy and in the research which is been carried out by researchers to explore more about stem cell treatment.

Induced pluripotent stem cells (iPSCs)

Induced pluripotent stem cells (iPSCs) are adult cells. They have been changed to act like ESCs. About 15 years ago, scientists discovered that they could change the genes of an adult cell such as a skin or a blood cell and turn it into an iPSC. iPSCs can make all cell types. Above all they can be made in the laboratory so there is an unlimited supply of them.

Adult stem cells

Adult stem cells are found in small numbers in many tissues. They can turn into a few but not all types of cells. Some adult stem cells, like bone marrow stem cells, which make blood and immune cells, or corneal limbal stem cells, help tissues cure and regenerate. Adult stem cells exist in the retina. They are called retinal progenitor cells. In the body, retinal progenitor cells don’t normally make new retinal cells even if there is damage. But researchers have been able to encourage them to make new retinal cells in the laboratory. Adult stem cells are being studied as treatments for blindness and mainly “Mesenchymal stem cells (MSCs)” are being used in different clinical trials to treat such eye blind cases and very much effective and getting good success rate.

STEM CELL THERAPY FOR VISION LOSS

There is a lot of excitement carried out about stem cell therapy as a treatment for vision loss because a single stem cell therapy may be able to treat different eye diseases. Stem cell therapy could also be useful for individuals whose disease is very premature and there is a lot of cell injury.

Examples of how stem cells are being used for vision loss:

• Corneal limbal stem cells from a donor or the patient’s other eye are used for the treatment of some types of corneal damage or disease.

Moreover, Researchers at the Centre for Genomic Regulation (CRG) in Barcelona are working to advance the stem cell treatment for retinal degeneration.

Holoclar® is currently the only clinically approved stem cell treatment for the eye. This treatment restores vision to patients with damaged corneas (the clear outermost part of the eye) by transplanting lab-grown limbal stem cells into areas of the eye lacking these cells.

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Myth# 1: All stem cells are the same 

People usually think of Embryonic Stem Cells when they hear the word “Stem Cells.” Many people are unaware that stem cells can come from a variety of places. Embryonic stem cells are pluripotent, meaning they can transform into any cell type in the body. They come from embryos. Adult stem cells are derived from postnatal human body reservoirs such as bone marrow and adipose tissue, umbilical cord tissue, teeth or dental pulp, etc.

Depending on their source, age, and other factors, these have varying abilities to become various types of cells in the body. Adult, completely differentiated cells, such as white blood cells and skin cells, are manipulated to become Embryonic-Like Stem Cells with very high pluripotency capabilities, which are then induced to reprogram back to become Induced Pluripotent Stem Cells. Adult or induced Pluripotent Stem Cells are used in the majority of experimental therapies and translational studies these days.

Myth#2: The use of Stem cell is unethical 

We tend not to take sides in public discussions on these kinds of ethical issues, but this is also a myth. Since they are derived from human embryos, Embryonic Stem Cells have sparked a great deal of ethical debate. However, in recent years, the medical research community has shifted its focus away from this contentious area and toward the use of adult and induced pluripotent stem cells in the treatment of diseases. Indeed, all of these initiatives made it through clinical trials with flying colours in terms of protection and efficacy. Adult stem cells and induced pluripotent stem cells are overwhelmingly preferred in current experimental therapies and studies, as we discussed in the previous article. Adult stem cells and induced pluripotent stem cells, it turns out, are not only ethically clear (because they’re made from donated material from a consenting adult, typically the person receiving treatment), but they also seem to be more successful and have no side effects.

Myth #3: Stem Cell therapy carries the risk of rejection.

This is misleading. The chance of rejection is almost non-existent because the medical community is focused on the use of autologous (from one’s own) Adult and induced Pluripotent Stem Cells for therapy. And allogenic (derived from non-self, exogenous) stem cells used in clinical trials have been shown to induce no immune response, as these MSCs have HLA-DR negligibe that means no chance to get any rejection or side effect. The most significant hindrance to these treatments reaching the general population is the very remote chance that these cells will become cancerous. Recent advances in stem cell science, on the other hand, demonstrate an exceptional level of control in the generation of these cells, which helps to ensure cancer-free stem cell therapy.

It is our duty to enlighten you with the verified data. Stem cell therapy appears like a miracle to the 21st century.  Keep reading us and get all the details related to stem cell and stem cell therapy.

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THE MAIN PARTS OF EYE ARE

Cornea– It is the transparent, anterior or front part of our eye. The main function is to refract the light along with the lens.

Lens– It is a transparent, biconvex, lens of an eye. The lens is attached to the ciliary body by ligaments.

Retina– It is the innermost layer of the eye. It is light sensitive and acts as a film of a camera. 

Optic nerve- Optic nerve encodes the image data recorded by the retina in the form of neural signals that can be read by the brain.

Retinal pigment epithelium- A sheet of black cells that sit beneath the retina. This sheet supports the retina and has a number of important roles, including processing nutrients.

Disorder or disease occurs when one or more than one of these components gets damaged. Different disorders damage different cells of the eye. Here comes the role of stem cell treatment. Different stem cells or specialized cells are used to cure the damage depending on the type of disorder. 

Do you know? 

The variety of stem cells present in the eye helps to replace the damaged or worn-out cells. Even blinking damages the surface of eye but it a good thing that stem cell is present to replenish it. 

Optic Nerve Atrophy 

Optic Nerve atrophy that means connectivity in between brain to eye has been damagedwhich is not possible to regenrate by itslef and Glaucoma (high eye prresure) and any brain injury or brain tumor surgery are the main cause to damage optic nerve cells of eye. Stem cell treatment plays a very good role to regenrate opric nerve cells and makes optic nerve moe healthy and regenerative and enhance some vision back.

Retinal and Macular disorders 

Several diseases are marked by retinal degeneration that eventually leads to blindness. Retinal disorders commonly involve the loss of photoreceptor cells which comes in Retinitis Pigmentosa disease, which depletes the eye’s rod and cones cells (responsible fro day and night vision). In some retinal disorders, including age-related macular degeneration (AMD), this loss results from the failure of the epithelial cells that form a layer at the back of the retina known as the retinal pigment epithelium (RPE). The RPE keeps photoreceptor cells healthy by cleaning up toxic by-products produced during the reaction with light, as well as by providing nutrients. In retinal disorders in which photoreceptors remain in good shape, the main cause of blindness is degeneration of retinal ganglion cells.

STEM CELL THERAPY 

Here the question comes can blindness be cured? 

 You might have heard about stem cell therapy and wondered if it could help you or someone you know who is living with vision loss. To help answer your questions, we’ve put together some information about stem cell treatment and how it helps to cure blindness. 

Stem cell therapy for the eye is getting headlines as they are the potential to cure diseases for which there are no other treatments. Stem cell treatment for the eye is collecting a lot of attention because of its success rate. 

Stem-cell therapy could potentially cure blindness even in the late stages of the disease. Because stem cells can be coaxed into becoming any type of cell, they could be used to grow fresh retinal cells for transplantation into the eye to replace those that have been lost.

THREE MAIN TYPES OF STEM CELLS ARE USED IN VISION TREATMENT 

Embryonic stem cells (ESCs)

Embryonic stem cells (ESCs) are pluripotent, which means they can become any type of cell in the body. Because of this ability, ESCs have been very important in stem cell therapy and in the research which is been carried out by researchers to explore more about stem cell treatment.

Induced pluripotent stem cells (iPSCs)

Induced pluripotent stem cells (iPSCs) are adult cells. They have been changed to act like ESCs. About 15 years ago, scientists discovered that they could change the genes of an adult cell such as a skin or a blood cell and turn it into an iPSC. iPSCs can make all cell types. Above all, they can be made in the laboratory so there is an unlimited supply of them.

Adult stem cells

Adult stem cells are found in small numbers in many tissues. They can turn into a few but not all types of cells. Some adult stem cells, like bone marrow stem cells, umbilical cord tissue and adipose derivd stem cells, which can create almost all type of organ specific cells and also helpful to regenrate almost all type of eye cells. Adult stem cells exist in the retina. They are called retinal progenitor cells. In the body, retinal progenitor cells don’t normally make new retinal cells even if there is damage. But researchers have been able to encourage them to make new retinal cells in the laboratory. Adult stem cells are being studied as treatments for blindness. 

STEM CELL THERAPY FOR VISION LOSS

There is a lot of suggestions carried out about stem cell therapy as a treatment for vision loss because a single stem cell therapy may be able to treat different eye diseases. Stem cell therapy could also be useful for individuals whose disease is very premature and there is a lot of cell injury. 

Examples of how stem cells are being used for vision loss:

• Corneal limbal stem cells from a donor or the patient’s other eye are used for the treatment of some types of corneal damage or disease.
• Retinal degeneration in diseases like AMD, retinitis pigmentosa, or choroideremia can be the result of different factors. But ultimately it leads to the death of the light-sensing photoreceptor cells as well as their support cells, retinal pigment epithelial (RPE) cells. Scientists have had the most success in making and transplanting RPE cells and clinical trials are testing if RPE cells, made from ESCs or iPSCs can improve vision for individuals with retinitis pigmentosa, Stargardt disease, or dry AMD.

Moreover, Researchers at the Centre for Genomic Regulation (CRG) in Barcelona are working to advance the stem cell treatment for retinal degeneration.

Holoclar® is currently the only clinically approved stem cell treatment for the eye. This treatment restores vision to patients with damaged corneas (the clear outermost part of the eye) by transplanting lab-grown limbal stem cells into areas of the eye lacking these cells.

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